Publication – STEPVAC

Eplasty An Open access Journal

Many studies are emerging attempting to show decreased rates of complications in patients using INPWT. ………………However, this review suggests the use of INPWT is a safe, well-tolerated intervention that may offer clinical benefit.

Diabetic Foot & Ankle 2013

As the prevalence of diabetes mellitus continues to rise, …………
…….challenging clinical case scenarios is Charcot neuroarthropathy associated …………authors present a review of the most common utilizations of negativepressure
wound therapy as an adjunctive therapy or combined with plastic surgery as it relates to the surgical management of diabetic Charcot foot and ankle wounds

Assessing a Safe Interval for Subsequent Negative Pressure Wound Therapy

Conclusions. Based on the findings in this study, analyzing NPWT in the largest known patient cohort of this type, a time interval of 1.7 days to 4.1 days (mean time 2.9 days, SD 1.24), between initial and subsequent placement of NPWT in acute, contaminated wounds is safe and effective.

Negative Pressure Wound Therapy: A Clinical Review

Many studies are emerging attempting to show decreased rates of complications in patients using INPWT. ………………However, this review suggests the use of INPWT is a safe, well-tolerated intervention that may offer clinical benefit.

Plastic Surgery International

Negative pressure wound therapy literature review of efficacy, cost effectiveness, and impact on patients’ quality of life in chronic wound management and its implementation in the United kingdom.

International Orthopaedics

Negative pressure wound therapy to prevent seromas and treat surgical incisions after total hip arthroplasty.

Journal of Cardiothoracic Surgery

Wound contraction and macro-deformation during negative pressure therapy of sternotomy wounds.

Eplasty. 2010; 10:

Wound chemotherapy by the use of negative pressure wound therapy and infusion.

ELSEVIER DOYMA

Negative-pressure wound therapy versus standard wound dressing in the treatment of diabetic foot amputation.[ A randomised controlled trial].

Bone & Joint Research Journal

Assisted closure of fasciotomy wounds A descriptive series and caution in patients with vascular injury

Romanian Society of Surgery Magazine

Continuous Negative Pressure Wound Therapy in the Treatment
of a Gigantic Trophic Leg Ulcer

Interactive CardioVasc Thorac Surg

Negative-pressure wound therapy for deep sternal wound infections reduces the rate of surgical interventions for early re-infections.

Eplasty. 2010; 10:

Wound chemotherapy by the use of negative pressure wound therapy and infusion.

Wound coverage considerations for defects of the lower third of the leg

Extract from “Wound coverage considerations for defects of the lower third of the leg”

INDIAN JOURNAL OF PLASTIC SURGERY Year : 2012 | Volume : 45 | Issue : 2 | Page : 283-290

Babu Bajantri, R Ravindra Bharathi, S Raja Sabapathy, Department of Plastic, Hand and Reconstructive Microsurgery and Burns, Ganga Hospital, Mettupalayam Road, Coimbatore, Tamil Nadu, India

VAC or vacuum-assisted closure, otherwise called NPWT (negative pressure wound therapy) has been used extensively in complex wounds of the lower limb either as an interim measure before the definitive cover or as a definitive therapy to achieve wound cover by forming granulation tissue over the implants and exposed bones over which a skin graft can be applied. In a retrospective study published in 2006 by Parrett et al., [11] they found a changing trend in the use of free flaps in a period of 12 years. Free flaps decreased from 42% over the first period to 11% in the last 4 years when VAC was extensively used. They have said that there is no statistically significant difference in infection, amputation and malunion/non-union rates. Bhattarcharyya [12] studied the infection rate in 38 patients with Grade III B open fractures treated with NPWT to see if the definitive time for wound closure can be extended beyond the conventionally held view of 7 days. There was an increase of infection rate from 12% to 57% despite the use of negative pressure. Although the study is small, this does suggest a degree of caution in using NPWT as a delaying tactic in lower extremity trauma and suggests that the strategy of trying to close these wounds within 7 days is still essential in the era of negative pressure wound therapy.

Improved wound management by regulated negative pressure-assisted wound therapy..

REVIEW ARTICLE – INDIAN JOURNAL OF PLASTIC SURGERY

Year : 2012 | Volume : 45 | Issue : 2 | Page : 291-301, Moris Topaz,

Plastic Surgery Unit, Hillel Yaffe Medical Center, Hadera, Department of Chemistry, Bar Ilan University, Ramat Gan, Israel

Regulated negative pressure-assisted wound therapy (RNPT) should be regarded as a state-of-the-art technology in wound treatment and the most important physical, nonpharmaceutical, platform technology developed and applied for wound healing in the last two decades.RNPT systems maintain the treated wound’s environment as a semi-closed, semi-isolated system applying external physical stimulations to the wound, leading to biological and biochemical effects, with the potential to substantially influence wound-host interactions, and when properly applied may enhance wound healing. RNPT is a simple, safe, and affordable tool that can be utilized in a wide range of acute and chronic conditions, with reduced need for complicated surgical procedures, and antibiotic treatment. This technology has been shown to be effective and safe, saving limbs and lives on a global scale. Regulated, oxygen-enriched negative pressure-assisted wound therapy (RO-NPT) is an innovative technology, whereby supplemental oxygen is concurrently administered with RNPT for their synergistic effect on treatment and prophylaxis of anaerobic wound infection and promotion of wound healing. Understanding the basic science, modes of operation and the associated risks of these technologies through their fundamental clinical mechanisms is the main objective of this review.
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Wound bed preparation from a clinical perspective

REVIEW ARTICLE INDIAN JOURNAL OF PLASTIC SURGERY Year : 2012 | Volume : 45 | Issue : 2 | Page : 193-202 AS Halim, TL Khoo, AZ Mat Saad,
Department of Reconstructive Sciences, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia

Wound bed preparation has been performed for over two decades, and the concept is well accepted. The ‘TIME’ acronym, consisting of tissue debridement, i nfection or inflammation, moisture balance and edge effect, has assisted clinicians systematically in wound assessment and management. While the focus has usually been concentrated around the wound, the evolving concept of wound bed preparation promotes the treatment of the patient as a whole. This article discusses wound bed preparation and its clinical management components along with the principles of advanced wound care management at the present time. Management of tissue necrosis can be tailored according to the wound and local expertise. It ranges from simple to modern techniques like wet to dry dressing, enzymatic, biological and surgical debridement. Restoration of the bacterial balance is also an important element in managing chronic wounds that are critically colonized. Achieving a balance moist wound will hasten healing and correct biochemical imbalance by removing the excessive enzymes and growth factors. This can be achieved will multitude of dressing materials. The negative pressure wound therapy being one of the great breakthroughs. The progress and understanding on scientific basis of the wound bed preparation over the last two decades are discussed further in this article in the clinical perspectives.

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